Important paper out on #Wuhan #nCoV2019 via @biorxivpreprint
— Andy Biotech (@AndyBiotech) January 23, 2020
96% sequence identity to a bat #coronavirus
~80% sequence identity to SARS
~95% AA sequence identity in 7 conserved replicase domains to SARS
uses the same cell entry receptor, ACE2, as SARShttps://t.co/iwaHTsDGJN pic.twitter.com/dGEjBvGx4j
This is major progress in understanding #Parkinsons disease biology!
— Chasing Kinases (@ChasingKinases) January 7, 2020
~ #LRRK2 atomic resolution #cryoEM structure
~ Switch between active / inactive conformations
~ Role of disease mutants
~ #LRRK2 blocks cargo transport along microtubuleshttps://t.co/k8jaEQoxoB pic.twitter.com/VUiOMAB6cH
This mind-blowing 3D super-resolution preprint is finally published in @sciencemagazine today as its cover story!https://t.co/ivvI15j180
— Andy Biotech (@AndyBiotech) January 17, 2020
The details of these nanoscale ultrastructures are simply stunning...
Congrats @davephoffman @SoleckiLab @HHMIJaneliahttps://t.co/dxuxo4pSKk pic.twitter.com/ATktiVPZkJ
Just published! Our 2020 Cancer Statistics article reveals a 2.2% decline in cancer mortality from 2016 to 2017—the largest single-year drop ever reported. https://t.co/mNdmxMnOJH @ACSNews pic.twitter.com/RyAxe6aFJE
— CA: A Cancer Journal for Clinicians (@CAonline) January 8, 2020
Oh man, cancers are just too damn smart...
— Andy Biotech (@AndyBiotech) January 9, 2020
Why KRAS(G12C) inhibitors result in only partial responses w/ rather short durability? $AMGN $MRTX $JNJ $LLYhttps://t.co/mIF9sPDT3U
"Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition"https://t.co/JJRt6ClRBD pic.twitter.com/3ghHZMooBA
AAV vectors may integrate in host genome... in dogs. Should gene therapy community be worried about humans? https://t.co/RSLD1nIx3H "...doubts about AAV’s safety have simmered for nearly 20 years"
— Alexey Bersenev (@cells_nnm) January 6, 2020
The inaugural @NatureCancer article is now online.
— Anirban Maitra (@Aiims1742) November 18, 2019
From @SanofiUS & crew: preclinical studies of TRISPECIFIC antibodies to enhance the efficacy of tumor directed T cells via incorporating costimulation.
Broke: BiTE
Woke: TriTE https://t.co/rEszuRoXpo pic.twitter.com/IOYgWaQE96
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