Chen and Beckman. Clinical Cancer Research.
The Imperative of Overcoming Barriers to the Conduct of Large, Simple Trials
Eapen, Lauer, and Temple. JAMA.
Correspondence regarding "Phase 3 Trials of Solanezumab and Bapineuzumab for Alzheimer's Disease"
Various authors debate. New England Journal of Medicine.
Changing a Broken Science System
Derek Lowe (In the Pipeline) reviews the provacative PNAS paper
The Calculus of Cures
Kocher and Roberts. New England Journal of Medicine.
Thoughts on reforming drug development in terms of cost, timeline, and approval standards.
U.S. Food and Drug Administration Inspections of Clinical Investigators: Overview of Results from 1977 to 2009
Morgan-Linnell et al. Clinical Cancer Research.
Valuable repository of data on FDA inspections of clinical trial investigators and conduct - and the outcomes/findings.