"In addition, under the terms of our agreement with Momenta Pharmaceuticals, we recently selected a third biosimilar for development, a monoclonal antibody for oncology designated as M511. This is in addition to the selection of M923 and M834 targeted for the treatment of autoimmune and other inflammatory disorders. As you know, Baxter and Momenta had the opportunity to develop up to 6 biosimilars through our partnership."
We are not likely to get much in the way of specifics anytime soon, but Momenta Pharma $MNTA partner Baxter BAX had this brief update about the status of their biosimilars/follow-on biologics (FOBs) collaboration on their recent earnings call (excerpt via SeekingAlpha):
"In addition, under the terms of our agreement with Momenta Pharmaceuticals, we recently selected a third biosimilar for development, a monoclonal antibody for oncology designated as M511. This is in addition to the selection of M923 and M834 targeted for the treatment of autoimmune and other inflammatory disorders. As you know, Baxter and Momenta had the opportunity to develop up to 6 biosimilars through our partnership."
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Continue reading below for the latest news and updates from Senomyx SNMX partners Pepsico and Nestle related to the research, development, and commercialization agreements in place for sweet and savory flavor ingredients for food and beverage products.
Both Aegerion Pharma AEGR (lomitapide) and Isis Pharma ISIS (KYNAMRO/mipomersen with partner Sanofi SNY / Genzyme) will face FDA advisory committees for the homozygous familial hypercholesterolemia (HoFH) drugs this week:
I compiled a few key figures from the FDA briefing document for AEGR, highlighted my notes from the FDA reviewers, and added a few comments of my own that relate to the panel discussions for both AEGR and ISIS. Sorry it is a bit disorganized, but I will try to go back and clarify further - keep reading here for all the details. GlaxoSmithKline $GSK and Ligand Pharma $LGND face a late November FDA PDUFA date (priority review) for their sNDA seeking approval of PROMACTA (eltrombopag) for the treatment of HCV-related thrombocytopenia. See below for abstracts accepted for presentation at AASLD 2012 in November. Also check out the first data presentation for Ligand's internal HCV program.
In its acquisition of Metabasis $MBRX, Ligand Pharma $LGND acquired the HepDirect liver-targeting technology. While some of these assets were licensed to Chinese biotech Chiva, some internal R&D remained. We for the first time see data on their guanosine nucleoside prodrug LG-7501 - see complete details below.
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