There's lots of great #immunology in @sciencemagazine this week! @JSRustenhoven & @jonykipnis (@kipnislab @UVA) author a fascinating Perspective on how immune cells bypass the blood–brain barrier!https://t.co/6QjcNxU0p6 pic.twitter.com/njjnrn9Yej
— Seth Thomas Scanlon (@ImmunoEditor) December 20, 2019
A phase 3 trial of anifrolumab showed benefit in a composite primary endpoint of lupus scores. A previous phase 3 trial failed to meet its primary endpoint but showed effect in secondary endpoints. https://t.co/PwZnsZa4Ud
— NEJM (@NEJM) December 18, 2019
Here's a new collection of reviews on #celltherapies https://t.co/3KOylu76j2 - covering regulatory T cells for immune disorders, gamma delta T cells for cancer and HSCs for blood disorders. Apologies for any issues with free access - these have been fixed @lzamparo @PDRennert pic.twitter.com/059Gos8ndB
— Nature Rev Drug Disc (@NatRevDrugDisc) December 2, 2019
Special issue of @sciencemagazine on quality control mechanisms that keep our cells healthy and maintain optimal performance
— Andy Biotech (@AndyBiotech) November 15, 2019
Ubiquitin-Proteasome Systemhttps://t.co/0v2fMXh3Xz
RNA surveillancehttps://t.co/VynqAObkYL
Mitochondria-cellular communicationhttps://t.co/CfNPwNeCHr pic.twitter.com/lWrlfJ9sIm
Using a smartphone app, investigators recruited 419,297 participants to be monitored for irregular pulses. Patterns suggesting atrial fibrillation were detected in 2161 participants who then received ECG monitoring devices. Read the Apple Heart Study. https://t.co/QhXpHzqcVL
— NEJM (@NEJM) November 13, 2019
One step closer to check STAT3 off the “Undruggable” list?
— Andy Biotech (@AndyBiotech) November 13, 2019
Inhibit vs Destroy: Are PROTAC Degraders the Solution to Targeting STAT3?https://t.co/JFUNJf0qE7
A Potent & Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivohttps://t.co/ZUu7oVBEnD pic.twitter.com/8zqDg6dSXw
$VRTX #CysticFibrosis triple combo Trikafta Ph3 data in @NEJM & @TheLancet https://t.co/0jyOYFEuFe https://t.co/4oeU11xSmO
— Andy Biotech (@AndyBiotech) October 31, 2019
NEJM Editorial by @NIHDirector on this 30-yr journey including an amazing diary of an 8yo girl from 1989https://t.co/kZTnogoguPhttps://t.co/ijUUMhYBmk pic.twitter.com/BY5x0U0EbF
This paper turned out to be very cool, especially after $RHHBY started their whole "Brain shuttle" project .
— Bursatil Biotech (@BursatilBiotech) October 16, 2019
Check it out @BertrandBio@JacobPlieth https://t.co/EC6zx1qxNq
On the occasion of his extremely well deserved Nobel Prize for co-discovery of oxygen sensing pathways, I recommend that everyone read his Nature commentary: Publish Houses of Brick, Not Mansions of Straw. Right on target. https://t.co/kDPcAMMjhH https://t.co/kC0V56R4bE
— Jeffrey Flier (@jflier) October 7, 2019