Metabolic Stress, Autophagy, and Cardiovascular Aging: from Pathophysiology to Therapeutics https://t.co/FKYSiZ5jtf
— Ethan Weiss (@ethanjweiss) September 18, 2018
expect the hacking of IgG and FcR to continue - this is a neat paper showing that membrane-bound IgG1 signaling can influence immune response (w/ obligatory lupus connection)https://t.co/9qBA50bVFf https://t.co/J7DDvcgD5I
— Paul D. Rennert (@PDRennert) October 5, 2018
Interesting data in NEJM on childhood #obesity
— Andy Biotech (@AndyBiotech) October 4, 2018
- obesity onset occurs early in life
- biggest weight gain occur b/t 2~6yrs old
- obesity then persists into adolescence
This could add more fuel to the nature vs. nurture debate?https://t.co/YTuybDBAib https://t.co/m94VFij3yQ pic.twitter.com/j6GnhUGjih
A new approach to define root cause of #Alzheimers disease https://t.co/2E5u4F59NM
— Eric Topol (@EricTopol) September 29, 2018
using chemical kinetics to define toxicity of misfolded proteins@PNAS by @mvendruscolo14 and colleagues @Cambridge_Uni @lunduniversity #OA pic.twitter.com/g2hLKinjRl
Tumors cleverly hide a piece of human leukocyte antigen in order to evade surveillance https://t.co/RDLlObmn90 MOA still unclear, but not a leap to imagine targeting this process to remove the invisibility cloak on tumors that have learned resistance so T-cells can resume killing
— David Maizenberg (@biologypartners) September 24, 2018
Here comes genome editing in mitochondria, which appear to be off-limits to #CRISPR https://t.co/z6cqYlieoI$SGMO mtZFNhttps://t.co/rj3FRfe9bA$CLLS MitoTALEN https://t.co/OHBJ6PbbrW pic.twitter.com/ETuYTpqMzo
— Andy Biotech (@AndyBiotech) September 24, 2018
Worth paying attention to:
— Michael Torres, PhD (@Mykalt45) September 19, 2018
Tools for translation: non-viral materials for therapeutic mRNA deliveryhttps://t.co/4OcG4oZhEI@KWhiteheadLab
This is fascinating. APOE4, at least in mice, may be involved in limiting the brain's ability to control blood flow. The gene variant increases the risk of Alzheimer's.https://t.co/1t3diR1zCJ
— Matthew Herper (@matthewherper) September 19, 2018
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