blockbuster review re. targeting BCMA for treatment of multiple #myeloma - via #bispecific #trispecific #ADC #CARTcell and etc etc and #openaccesshttps://t.co/QlCP3maFK0
— Paul D. Rennert (@PDRennert) September 12, 2018
h/t @BiotechRadar
$BMY TYK2 inhibitor psoriasis data out in NEJM: impressive efficacy, safety look quite clean toohttps://t.co/n9RrLCIcV7
— Andy Biotech (@AndyBiotech) September 12, 2018
A few other interesting derm datasets coming at #EADV18 this wk$PFE JAK3i & TYK2/JAK1i in alopecia -> $CNCE $ACRS$KNSA OSMRβi in AD
BI anti-IL-36R in GPP pic.twitter.com/UH8uLlxCT1
Basic review of cancer clinical trial statistics. Very good resource for savy patients, non-oncology physicians and, of course...new oncology fellows! https://t.co/NAd6rki8BB
— Andy Laccetti MD (@alaccetti) September 8, 2018
One of the more interesting data today
— Andy Biotech (@AndyBiotech) September 5, 2018
Eureka’s TCR-mimic CAR-T targeting intracellular/secreted alpha-fetoprotein (AFP) achieved a completed response in tough liver cancer in its PoC trial in Chinahttps://t.co/FTajEs0tHG
Preclinical data in CCRhttps://t.co/AhRHlzsgZQ pic.twitter.com/BmLQPK2O3j
Depression and inflammation https://t.co/0B0YqG4cHB
— Alfredo Fontanini (@AF_biotech) August 28, 2018
$PFE Tafamidis Ph3 ATTR-ACT data out in NEJMhttps://t.co/ygEk6fIuHMhttps://t.co/nQnSuVtUUK
— Andy Biotech (@AndyBiotech) August 27, 2018
- Primary endpt win ratio =1.70, p<0.001
- hit on all-cause mortality: HR=0.70
- Only hit stat sig in ATTR wild type, not in ATTR mutant patients#ESCcongress $EIDX $ALNY $AKCA $IONS pic.twitter.com/EkjXtUjyzj
2.8m deaths ww in 2016 attributable to alcohol use. Great article published in @TheLancet https://t.co/PY86Sxtg7c
— Juan P. Serrate, DVM (@JPZaragoza1) August 23, 2018
Read the new Cancer Discovery review article by James Allison and colleagues: Fundamental Mechanisms of Immune Checkpoint Blockade Therapy #Immunotherapy @MDAndersonNews https://t.co/bEiyoRqxvO pic.twitter.com/brBOAHAYHz
— AACR (@AACR) August 17, 2018
Loss of gut barrier integrity is considered to contribute to inflammation #IBD #obesity, and metabolic disorders #NASH A primary or secondary event in pathogenesis? Worth targeting in humans? https://t.co/Heen0uA4hS
— Daniel J Drucker (@DanielJDrucker) August 17, 2018
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice https://t.co/COVYsFOkvy #genomeediting #genetherapy pic.twitter.com/HLxEF9AVv2
— Nature Biotechnology (@NatureBiotech) August 13, 2018
Important assessment of polygenic risk scores for 5 common diseases@NatureGenet by @amitvkhera @skathire @broadinstitute @MGHResearch et alhttps://t.co/eRisYjpUtB
— Eric Topol (@EricTopol) August 13, 2018
Yes: "it is time to contemplate the inclusion of polygenic risk prediction in clinical care" pic.twitter.com/XeLh1V98he
Very important work!#CRISPR ‘barcodes’ map mammalian development in exquisite detailhttps://t.co/zGqt3YQa4L
— Andy Biotech (@AndyBiotech) August 10, 2018
Full developmental lineage record for every single cell in real-time https://t.co/QV38goJKKW pic.twitter.com/5xnWihYao8
OMG, it's finally out.. Thanks Nature for publishing our finding that large deletions could be frequently generated after Cas9 single cleavage in mouse zygotes and ES cells. https://t.co/GogdnlNSMl
— Fatwa Adikusuma (@Fatwa_Adikusuma) August 8, 2018
Does exercise reduce mental health burden, depression?
— Eric Topol (@EricTopol) August 8, 2018
The largest cross-sectional study ever says yes. And quantified by time and type of exercise. https://t.co/wEJFCsMGO6 @TheLancetPsych @itschekkers @hmkyale @srchekroud @YaleMed and collaborators pic.twitter.com/QVY2SwmUc4
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