(continue reading for full "link fest")
Progress and Promise: The Current Status of Spinal Muscular Atrophy Therapeutics
Good background if you are interested in the upcoming ISIS-BIIB data release (h/t @chasingthealpha)
Sequester Cuts Comes Down Hard on Scientific, Medical Research
As Sequestration Dawns, FDA Supporters Scramble to Ease Woes of Drug Reviews
Fierce Biotech
There Should be Grandeur: Basic Science in the Shadow of the Sequester
Scientific American - Tom Levenson (h/t @vero_greenwood)
FDA Reform Can Lift U.S. Economy
Bloomberg, h/t @MatthewHerper - interesting read even though the article is deeply flawed and I disagree with a number of their conclusions/suggestions
Finding Parallels in Baseball and Drug Development
Xconomy - Kyle Serikawa
FDA Breakthrough Therapy Designations - FAQ's and Statistics on Applications, Approvals, and Rejections
Great new feature on official FDA website (h/t @scrippdonnadc and @pinksheetsutter)
Inhibitors of Apoptosis Target one of the Hallmarks of Cancer
Biotech Strategy Blog by Pieter Droppert (@3NT)
Updates on drugs targeting IAP including from Roche/Genentech, Curis CRIS, Astex Pharma ASTX, Novartis NVS.
Cave Explorer Hunts Antibiotics1,600 Feet Down
Bloomberg - Meg Tirrell (h/t @bradloncar and re CBST, OPTR, etc in the antibiotics space)
FDA wants to regulate drug firms on the internet and it's targeting Facebook "Likes"
Forbes - Scott Gottlieb
More on the Shelf
Nature blogs - Adam Scott Bristol
What happens after a biotech company files a S-3 statement ("shelf")? Detailed analysis.
Roche peels back curtain on clinical trial data
Pharmalot - Ed Silverman. A second big pharma says they will make all data public. An important trend to monitor, with far-reaching potential consequences